![]() Symptoms have occurred in people with and without pre-existing psychiatric disease. Severe neuropsychiatric symptoms, including agitation, anxiety, delusions, hallucinations, panic disorder, paranoia, and psychosis have been reported with Wellbutrin (bupropion) and it carries a black box warning for these effects.May have also caused abdominal pain, abnormal dreams, flushing, muscle and joint pain, migraine, rash, or itchy skin. Insomnia, headache, dizziness, dry mouth, sore throat, nausea, and constipation were the more commonly reported side effects.If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Generic bupropion is available and bupropion is also marketed under other brand names such as Aplenzin (also for depression) and Zyban (for smoking cessation).Wellbutrin was used to relieve the symptoms of depression in Major Depressive Disorder (MDD) and Seasonal Affective Disorder (SAD).Bupropion is an aminoketone antidepressant and is chemically unrelated to any other type of antidepressant.Bupropion does not affect the reuptake of serotonin or inhibit monoamine oxidase. Experts aren't exactly sure how bupropion works in depression but presume it is due to its ability to inhibit the reuptake of two neurotransmitters, norepinephrine, and dopamine (although this reuptake inhibition is weak).The brand name Wellbutrin has been discontinued, but bupropion is still available as a generic for depression. Wellbutrin is a brand (trade) name for bupropion which is an antidepressant that may be used to treat Major Depressive Disorder (MDD) and Seasonal Affective Disorder (SAD).Medically reviewed by Carmen Fookes, BPharm.
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